Excessively high or low temperatures in an office area can also lead to symptoms in building occupants and reduce productivity. High temperatures have been associated with fatigue, lassitude, irritability, headache and decrease in performance, coordination and alertness. A number of factors interact to determine whether people are comfortable with the temperature of the indoor air. The activity level, age, and physiology of each person affect the thermal comfort requirements of that individual. Extreme heat, which is unlikely to be found in an office environment, can result in heat rash, exhaustion, and fainting. Workers who may be less alert or fatigued from a high temperature environment may be more prone to accidents.